AHS16 - Ancestral Health Symposium 2016

It is widely understood in the ancestral health community that an individual's genes may determine their response to varying foods. An estimated 1 in 6 people carry the homozygous minor alleles in the gene responsible for coding the APO A2 protein, resulting in a deviant response to foods containing saturated fat with regards to BMI, satiety, and CVD risk. The variations in the APO A2 gene has become one of the most researched gene-diet interactions to date. A review of the current body of literature, including a critical examination of methods used in various experiments, may serve attendees in learning how to determine whether they or their clients may carry the homozygous CC polymorphism, and what practical modifications to diet may be necessary to facilitate desirable satiety, body composition, and chronic disease risk.